Antibiotic prophylaxis in neutropenic patients.

نویسندگان

  • Anat Gafter-Gvili
  • Mical Paul
  • Abigail Fraser
  • Leonard Leibovici
چکیده

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منابع مشابه

Oral Ciprofloxacin Prophylaxis in Patients Undergoing High Dose Therapy and Autologous Hematopoietic Stem Cell Transplantation

Background: Antibiotic prophylaxis is usually used in allogenic stem cell transplantation, but its use in Autologous Stem Cell Transplantation (ASCT) is controversial. We evaluated the efficacy of ciprofloxacin prophylaxis in ASCT. Materials and Methods: To identify the efficacy of ciprofloxacin on the incidence of neutropenic fever and its complications, 72 patients had been admitted to Talegh...

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Oral Ciprofloxacin Prophylaxis in Patients Undergoing High Dose Therapy and Autologous Hematopoietic Stem Cell Transplantation

Background: Antibiotic prophylaxis is usually used in allogenic stem cell transplantation, but its use in Autologous Stem Cell Transplantation (ASCT) is controversial. We evaluated the efficacy of ciprofloxacin prophylaxis in ASCT. Materials and Methods: To identify the efficacy of ciprofloxacin on the incidence of neutropenic fever and its complications, 72 patients had been admitted to Talegh...

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Meta-analysis: antibiotic prophylaxis reduces mortality in neutropenic patients.

BACKGROUND Bacterial infections are a major cause of illness and death in patients who are neutropenic after chemotherapy treatment for cancer. Trials have shown the efficacy of antibiotic prophylaxis in decreasing the incidence of bacterial infections but not in reducing mortality rates. PURPOSE To evaluate whether antibiotic prophylaxis in neutropenic patients reduces mortality and incidenc...

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Ciprofloxacin prophylaxis in high risk neutropenic patients: effects on outcomes, antimicrobial therapy and resistance

BACKGROUND The use of quinolone prophylaxis in high-risk neutropenic patients is considered standard of care but the development of resistance is a concern. Previous studies have focused mainly on quinolone resistance among patients receiving prophylaxis, with very few data reporting its impact on the hospital microbial epidemiology. METHODS We analyzed a cohort of 329 episodes of chemotherap...

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Antibiotic Prophylaxis with Quinolones in Afebrile Neutropenic Patients: Is there Enough Evidence for Mortality Effect?

Febrile neutropenia causes significant morbidity and mortality in patients receiving antineoplastic chemotherapy. During the last decade, some trials have shown reduction in febrile episodes and bacteraemia with antibiotic prophylaxis. On the other hand, the emergence of fluoroquinolone-resistant bacteria in units practicing quinolones prophylaxis has been described and there is justified conce...

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عنوان ژورنال:
  • The Israel Medical Association journal : IMAJ

دوره 9 6  شماره 

صفحات  -

تاریخ انتشار 2007